Prolotherapy, also known as proliferation therapy, is an injection-based treatment used to address chronic musculoskeletal pain. At Venturis Clinic in Oklahoma City, we’ve seen promising results in patients dealing with conditions like low back pain, tendonitis, arthritis, and knee osteoarthritis.
But how effective is it really? And are there any risks? Let’s dive into the details so you can make an informed decision.
What Is Prolotherapy?
Prolotherapy involves injecting a natural irritant—typically a solution of dextrose (sugar) and Sodium Morrhuate (derived from cod liver oil)—into injured joints, ligaments, or tendons. This triggers the body’s natural healing response, promoting the growth and strengthening of connective tissues.
The treatment is typically administered with a local anesthetic such as lidocaine, procaine, or marcaine to reduce discomfort during the injection.
How Effective Is Prolotherapy?
While prolotherapy has been around since the early 1900s, it continues to gain traction as a safe and effective alternative for treating chronic pain, especially when conventional treatments fall short.
Conditions Commonly Treated:
- Low back pain
- Tendonitis
- Knee osteoarthritis
- Ligament injuries
- Arthritis in joints such as the hip, knee, or shoulder
Multiple research studies and clinical experiences have shown that prolotherapy can help reduce pain, improve joint stability, and enhance function—especially when performed by a skilled and experienced physician.
Most patients receive 4 to 10 injections over a period of 3 to 6 months, with injections spaced about 2 to 3 weeks apart.
Risks and Complications of Prolotherapy
Like any medical procedure, prolotherapy carries some risks—though serious complications are rare when performed correctly.
Common Side Effects:
- Temporary swelling or stiffness
- Mild pain or soreness at the injection site
- Headache
- Allergic reactions (though uncommon)
Rare but Serious Complications:
- Spinal fluid leak
- Pneumothorax (collapsed lung)
- Permanent nerve damage or paralysis (extremely rare)
One critical factor is who performs the treatment. Prolotherapy requires precision, training, and experience. It should only be administered by a qualified physician who understands the intricacies of joint anatomy and injection techniques.
Dr. Philipose at Venturis Clinic, for example, has performed over 1,000 prolotherapy injections over the past 21 years, using advanced diagnostic imaging and thorough physical exams to ensure optimal outcomes.
Important Post-Treatment Guidelines
To minimize discomfort and reduce the risk of complications, patients are advised to:
- Avoid aspirin and anti-inflammatory medications (they can interfere with the healing response)
- Apply ice to the treated area 3–5 times a day for 15–20 minutes
- Engage in light to moderate exercise, but avoid heavy lifting or high-impact activities during recovery
Final Thoughts
Prolotherapy can be an excellent option for those dealing with chronic joint or ligament pain—especially when other treatments haven’t worked. However, the key to success lies in working with an experienced provider who understands how to safely and effectively administer the therapy.
If you’re in the Oklahoma City area and want to explore prolotherapy as a treatment option, Venturis Clinic is here to help. With decades of experience and a focus on regenerative and integrative medicine, our team is committed to helping you find long-lasting relief.
📞 Call 405-698-4027 or schedule a consultation online to learn more about prolotherapy and whether it’s right for you.