Ozone IV Therapy for Immune Support, Oklahoma City, OK

IV ozone therapy, also called major autohemotherapy (MAH), is the most widely used and most studied way to give ozone throughout the body. A measured amount of your blood is drawn into a sterile container, mixed with a precise ozone-oxygen dose, and returned through the same IV. At Venturis Clinic in Oklahoma City, it is offered only after a Good Faith Exam and lab screening.

This page explains how IV ozone works, who it may suit, who should not have it, and what a visit looks like. For every ozone option we offer, see ozone therapy in Oklahoma City.

Ozone therapy is investigational and is not approved by the U.S. Food and Drug Administration to treat, cure or prevent any disease. This page is general education, not medical advice. Individual results vary.

How IV ozone therapy works

Ozone (O₃) is a reactive form of oxygen. When a small, controlled dose meets blood outside the body, it reacts within seconds and forms short-lived signaling molecules. The working theory is that these signals prompt the body to step up its own antioxidant, circulation and repair responses, a hormetic effect similar to how exercise, a mild stress, leads the body to adapt.

That is a reasonable, well-described hypothesis supported by laboratory and early clinical research. Larger, high-quality human trials are still limited, which is why we describe ozone as investigational rather than promising results.

Important: ozone gas is never injected directly into a vein. It is mixed with blood outside the body in a closed, sterile system, and the blood is returned. Direct IV injection of gas is unsafe and is not used at Venturis.

Who may consider IV ozone

People who ask us about IV ozone are often dealing with long-running, hard-to-explain health problems. Depending on your Good Faith Exam, IV ozone may be discussed as one supportive option for people with:

• lingering fatigue after a viral illness, including long COVID,
• mold-related illness or CIRS,
• a history of Epstein-Barr reactivation, or
• general wellness goals, alongside nutrition, sleep and other foundations.

It is supportive care, not a replacement for your primary doctor or specialists.

Who should not have IV ozone

IV ozone is generally not given to people with G6PD deficiency, pregnancy, uncontrolled hyperthyroidism, low platelets or bleeding disorders, a recent heart attack or stroke, or acute alcohol intoxication. Blood thinners and some medications change the plan. Read ozone therapy side effects and safety for details.

What a visit looks like

1. Good Faith Exam with a licensed provider: history, medications and goals.
2. Labs, including G6PD screening and usually a recent blood count (lab testing at Venturis).
3. IV placement in an arm vein.
4. Treatment. A measured volume of blood is collected, ozone made on site from medical-grade oxygen is added at a set concentration, and the blood is returned. Most sessions take about 45 to 60 minutes including setup.
5. Monitoring and aftercare. Most people go back to their day afterward.

Our ozone program was built by our founder, Alvin Philipose, who wrote the book Ozone Therapy: The Promising Science Behind Healing and Wellness and teaches ozone therapy to physicians and other practitioners. Treatments are performed by licensed medical staff under our medical director.

Side effects

The most common are bruising at the IV site, mild vein irritation, and feeling tired for the rest of the day. Serious problems are rare in screened patients treated with medical-grade equipment.

IV ozone, 10-pass and EBOO

Standard IV ozone treats one collected volume of blood at a time. “10-pass” ozone repeats that cycle many times in one session. EBOO therapy uses a continuous circuit with a filter to treat a much larger volume. A lower-intensity alternative that uses no blood is ozonated saline. Compare them in EBOO vs 10-pass vs IV ozone.

Cost

Cost is discussed at your consultation and depends on your plan. Venturis is direct-pay and does not bill insurance.

Frequently asked questions

Is IV ozone therapy the same as major autohemotherapy?

Yes. “Ozone IV” usually means major autohemotherapy: your blood is mixed with ozone outside the body and returned.

How many IV ozone sessions do people usually have?

There is no fixed number. A plan is set after your Good Faith Exam and adjusted based on how you respond.

Does IV ozone hurt?

It feels much like a blood draw and an IV. Most people read or rest during the session.

Can I combine IV ozone with vitamin IVs?

Sometimes. Your provider decides the order and timing; some infusions are scheduled on separate days. See our IV therapy menu.

Is IV ozone covered by insurance?

No. Ozone therapy is investigational and is not covered by insurance.

Start with a conversation

Book a free 15-minute discovery call or call (405) 848-7246. Venturis Clinic, 7917 N. May Ave., Oklahoma City, OK 73120.